Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis
نویسندگان
چکیده
منابع مشابه
Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study.
BACKGROUND Type 2 diabetes mellitus (T2D) and cardiovascular disease share risk factors and subclinical atherosclerosis (SCA) predicts events in those with and without diabetes mellitus. T2D genetic risk may predict both T2D and SCA. We hypothesized that greater T2D genetic risk is associated with higher extent of SCA. METHODS AND RESULTS In a cross-sectional analysis, including ≤9210 Europea...
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چکیده ندارد.
15 صفحه اولIdentification of New Genetic Risk Variants for Type 2 Diabetes
Although more than 20 genetic susceptibility loci have been reported for type 2 diabetes (T2D), most reported variants have small to moderate effects and account for only a small proportion of the heritability of T2D, suggesting that the majority of inter-person genetic variation in this disease remains to be determined. We conducted a multistage, genome-wide association study (GWAS) within the...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2015
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.114.000740